CRISPR

CRISPR3-gdnfa

ID
ZDB-CRISPR-211025-6
Name
CRISPR3-gdnfa
Previous Names
None
Target
Sequence
5' - CTCAGGAGCAACAAACACG - 3'
ZFIN BLAST NCBI BLAST Ensembl
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
ot218 gdnfa
Expression
Gene expression in Wild Types + CRISPR3-gdnfa
No data available
Phenotype
Phenotype resulting from CRISPR3-gdnfa
No data available
Phenotype of all Fish created by or utilizing CRISPR3-gdnfa
Phenotype Fish Conditions Figures
diencephalon dopaminergic neuron decreased amount, abnormal AB + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa control Fig. 3 from Wong et al., 2020
whole organism gdnfa expression decreased amount, abnormal AB + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa control Fig. 2 from Wong et al., 2020
diencephalon dopaminergic neuron decreased amount, abnormal ot80Tg + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa (AB) chemical treatment by environment: N-methyl-4-phenylpyridinium Fig. 10 from Wong et al., 2020
whole organism otpa expression decreased amount, abnormal ot80Tg + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa (AB) control Fig. 6 from Wong et al., 2020
whole organism th expression decreased amount, abnormal ot80Tg + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa (AB) control Fig. 3 from Wong et al., 2020
whole organism lmx1bb expression decreased amount, abnormal ot80Tg + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa (AB) control Fig. 6 from Wong et al., 2020
locomotory behavior decreased process quality, abnormal ot80Tg + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa (AB) control Fig. 8 from Wong et al., 2020
whole organism shha expression increased amount, abnormal ot80Tg + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa (AB) control Fig. 6 from Wong et al., 2020
whole organism shha expression decreased amount, abnormal ot80Tg + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa (AB) control Fig. 6 from Wong et al., 2020
diencephalon dopaminergic neuron th expression decreased distribution, abnormal ot80Tg + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa (AB) control Fig. 4,  Fig. 5 from Wong et al., 2020
whole organism otpb expression decreased amount, abnormal ot80Tg + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa (AB) control Fig. 6,  Fig. 9 from Wong et al., 2020
diencephalon dopaminergic neuron EGFP expression decreased distribution, abnormal ot80Tg + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa (AB) control Fig. 4,  Fig. 5,  Fig. 9 from Wong et al., 2020
diencephalon cell population proliferation decreased process quality, abnormal ot80Tg + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa (AB) control Fig. 5 from Wong et al., 2020
whole organism nr4a2b expression decreased amount, abnormal ot80Tg + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa (AB) control Fig. 6 from Wong et al., 2020
whole organism neurog1 expression increased amount, abnormal ot80Tg + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa (AB) control Fig. 6 from Wong et al., 2020
whole organism nr4a2a expression decreased amount, abnormal ot80Tg + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa (AB) control Fig. 6 from Wong et al., 2020
dopaminergic neuron cell population proliferation decreased process quality, abnormal ot80Tg + CRISPR1-gdnfa + CRISPR2-gdnfa + CRISPR3-gdnfa + CRISPR4-gdnfa + CRISPR5-gdnfa (AB) control Fig. 5 from Wong et al., 2020
spinal cord otpa expression decreased distribution, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
preoptic area otpb expression decreased distribution, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
hindbrain nr4a2b expression decreased amount, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
caudal tuberculum otpb expression decreased amount, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
telencephalon otpb expression decreased amount, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
caudal tuberculum otpb expression decreased distribution, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
caudal tuberculum lmx1bb expression decreased amount, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
hindbrain lmx1bb expression decreased distribution, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
hindbrain lmx1bb expression decreased amount, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
caudal tuberculum lmx1bb expression decreased distribution, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
telencephalon otpb expression decreased distribution, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
hindbrain otpb expression decreased distribution, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
preoptic area otpb expression decreased amount, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
hindbrain nr4a2b expression decreased distribution, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
spinal cord otpa expression decreased amount, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
hindbrain otpb expression decreased amount, abnormal gdnfaot218/ot218; ot80Tg (AB) standard conditions Fig. 7 from Wong et al., 2020
Citations
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