CRISPR

CRISPR3-nrxn2a

ID

ZDB-CRISPR-211022-4

Name

CRISPR3-nrxn2a

Previous Names

None

Target

nrxn2a (1)

Sequence

5' - GGCACCGAGTTCTGCTGACC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ns15	nrxn2a

Expression

Gene expression in Wild Types + CRISPR3-nrxn2a

No data available

Phenotype

Phenotype resulting from CRISPR3-nrxn2a

No data available

Phenotype of all Fish created by or utilizing CRISPR3-nrxn2a

Phenotype	Fish	Conditions	Figures
myotome skeletal muscle cell decreased area, abnormal	nrxn2a^ns15/ns15	standard conditions	Fig. 5 from Koh et al., 2020
CaP motoneuron neuromuscular junction development process quality, abnormal	nrxn2a^ns15/ns15	standard conditions	Fig. 2, Fig. 4 from Koh et al., 2020
myotome skeletal muscle cell disorganized, abnormal	nrxn2a^ns15/ns15	standard conditions	Fig. 5 from Koh et al., 2020
whole organism decreased weight, abnormal	nrxn2a^ns15/ns15	standard conditions	Fig. 4 from Koh et al., 2020
CaP motoneuron axon guidance decreased process quality, abnormal	nrxn2a^ns15/ns15	standard conditions	Fig. 2 from Koh et al., 2020
whole organism startle response increased occurrence, abnormal	nrxn2a^ns15/ns15	standard conditions	Fig. 6 from Koh et al., 2020
CaP motoneuron axon increased branchiness, abnormal	nrxn2a^ns15/ns15	standard conditions	Fig. 2 from Koh et al., 2020
CaP motoneuron axon guidance decreased process quality, abnormal	nrxn2a^ns15/ns15	standard conditions	Fig. 2 from Koh et al., 2020
whole organism decreased length, abnormal	nrxn2a^ns15/ns15	standard conditions	Fig. 4 from Koh et al., 2020
CaP motoneuron axon increased branchiness, abnormal	nrxn2a^ns15/ns15	standard conditions	Fig. 2 from Koh et al., 2020
CaP motoneuron axon guidance decreased process quality, abnormal	nrxn2a^ns15/ns15	standard conditions	Fig. 2 from Koh et al., 2020
whole organism behavioral fear response increased occurrence, abnormal	nrxn2a^ns15/ns15	standard conditions	Fig. 6 from Koh et al., 2020
myotome atrophied, abnormal	nrxn2a^ns15/ns15	standard conditions	Fig. 5 from Koh et al., 2020
whole organism nrxn2a expression absent, abnormal	nrxn2a^ns15/ns15	standard conditions	Fig. 1 from Koh et al., 2020
CaP motoneuron axon extension involved in axon guidance delayed, abnormal	nrxn2a^ns15/ns15	standard conditions	Fig. 2 from Koh et al., 2020
CaP motoneuron axon guidance decreased process quality, abnormal	nrxn2a^ns15/+	standard conditions	Fig. 2 from Koh et al., 2020

Citations