Gene
nrxn2a
- ID
- ZDB-GENE-070206-5
- Name
- neurexin 2a
- Symbol
- nrxn2a Nomenclature History
- Previous Names
-
- nrxn2aa
- nrxn2ab
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity. Acts upstream of or within axon extension involved in axon guidance; chemical synaptic transmission; and motor neuron axon guidance. Predicted to be located in presynaptic membrane. Is expressed in nervous system and spinal cord neural tube. Orthologous to human NRXN2 (neurexin 2).
- Genome Resources
- Note
-
nrxn2a has two isoforms, alpha (DQ641428) and beta (DQ641429)
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001791 | Laminin G domain |
| Domain | IPR003585 | Neurexin/syndecan/glycophorin C |
| Domain | IPR027789 | Syndecan/Neurexin domain |
| Family | IPR050372 | Neurexin-related cell adhesion and synaptic protein |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
Domain Details Per Protein
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nrxn2a-201
(1)
|
Ensembl | 4,333 nt | ||
| mRNA |
nrxn2a-203
(1)
|
Ensembl | 6,930 nt | ||
| mRNA |
nrxn2a-204
(1)
|
Ensembl | 5,013 nt | ||
| ncRNA |
nrxn2a-003
(1)
|
Ensembl | 576 nt |
Interactions and Pathways
No data available
Plasmids
No data available