CRISPR

CRISPR3-uba1

ID

ZDB-CRISPR-210820-7

Name

CRISPR3-uba1

Previous Names

None

Target

Sequence

5' - GGTGAGGGTGCCAGTGTAGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
hg122	uba1

Expression

Gene expression in Wild Types + CRISPR3-uba1

No data available

Phenotype

Phenotype resulting from CRISPR3-uba1

No data available

Phenotype of all Fish created by or utilizing CRISPR3-uba1

Phenotype	Fish	Conditions	Figures
whole organism isg15 expression increased amount, abnormal	uba1^hg122/hg122; i114Tg	standard conditions	Fig. 4 from Beck et al., 2020
whole organism tnfa expression increased amount, abnormal	uba1^hg122/hg122; i114Tg	standard conditions	Fig. 4 from Beck et al., 2020
whole organism dead, abnormal	uba1^hg122/hg122; i114Tg	standard conditions	Fig. text only from Beck et al., 2020
whole organism il1b expression increased amount, abnormal	uba1^hg122/hg122; i114Tg	standard conditions	Fig. 4 from Beck et al., 2020
whole organism tnfb expression increased amount, abnormal	uba1^hg122/hg122; i114Tg	standard conditions	Fig. 4 from Beck et al., 2020
whole organism decreased life span, abnormal	uba1^hg122/hg122; i114Tg	standard conditions	Fig. text only from Beck et al., 2020
whole organism cxcl8a expression increased amount, abnormal	uba1^hg122/hg122; i114Tg	standard conditions	Fig. 4 from Beck et al., 2020
whole organism ifng1 expression increased amount, abnormal	uba1^hg122/hg122; i114Tg	standard conditions	Fig. 4 from Beck et al., 2020
neutrophil decreased amount, abnormal	uba1^hg122/hg122; i114Tg	standard conditions	Fig. S13, Fig. text only from Beck et al., 2020

Citations