CRISPR

CRISPR2-sox1a

ID

ZDB-CRISPR-200203-1

Name

CRISPR2-sox1a

Previous Names

None

Target

sox1a (1)

Sequence

5' - GGGTGGCTTGCTCGGCGGTG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
u5039	sox1a
ups8	sox1a

Expression

Gene expression in Wild Types + CRISPR2-sox1a

No data available

Phenotype

Phenotype resulting from CRISPR2-sox1a

No data available

Phenotype of all Fish created by or utilizing CRISPR2-sox1a

Phenotype	Fish	Conditions	Figures
dorsal habenular nucleus left side kctd8 expression increased amount, abnormal	sox1a^ups8/ups8; u711Tg; zf104Tg (AB/TL)	control	Fig. 3 from Lekk et al., 2019
dorsal habenular nucleus left side nrp1a expression decreased amount, abnormal	sox1a^ups8/ups8; u711Tg; zf104Tg (AB/TL)	control	Fig. 3 from Lekk et al., 2019
dorsal habenular nucleus neurogenesis decreased process quality, abnormal	sox1a^ups8/ups8; u711Tg; zf104Tg (AB/TL)	control	Fig. 6 from Lekk et al., 2019
dorsal habenular nucleus left side physical object quality, abnormal	sox1a^ups8/ups8; u711Tg; zf104Tg (AB/TL)	control	Fig. 6 from Lekk et al., 2019
parapineal organ neuron projection decreased length, abnormal	sox1a^ups8/ups8; u711Tg; zf104Tg (AB/TL)	standard conditions	Fig. 2 from Lekk et al., 2019
parapineal organ efferent neuron morphology, abnormal	sox1a^ups8/ups8; u711Tg; zf104Tg (AB/TL)	standard conditions	Fig. 2 from Lekk et al., 2019
habenula determination of left/right symmetry disrupted, abnormal	sox1a^ups8/ups8; u711Tg; zf104Tg (AB/TL)	standard conditions	Fig. 3 from Lekk et al., 2019
dorsal habenular nucleus left side kctd12.1 expression decreased amount, abnormal	sox1a^ups8/ups8; u711Tg; zf104Tg (AB/TL)	control	Fig. 3 , Fig. 6 from Lekk et al., 2019
pineal complex sox1a expression absent, abnormal	sox1a^ups8/ups8; u711Tg; zf104Tg (AB/TL)	control	Fig. 2 from Lekk et al., 2019
parapineal organ neuron projection decreased amount, abnormal	sox1a^ups8/ups8; u711Tg; zf104Tg (AB/TL)	standard conditions	Fig. 2 from Lekk et al., 2019
parapineal organ neuron projection decreased branchiness, abnormal	sox1a^ups8/ups8; u711Tg; zf104Tg (AB/TL)	standard conditions	Fig. 2 from Lekk et al., 2019
dorsal habenular nucleus left side slc18a3b expression increased amount, abnormal	sox1a^ups8/ups8; u711Tg; zf104Tg (AB/TL)	control	Fig. 3 from Lekk et al., 2019
parapineal organ sox1a expression absent, abnormal	sox1a^ups8/ups8; u711Tg; zf104Tg (AB/TL)	control	Fig. 2 from Lekk et al., 2019

Citations