CRISPR

CRISPR1-hdac4

ID

ZDB-CRISPR-190627-1

Name

CRISPR1-hdac4

Previous Names

None

Target

hdac4 (1)

Sequence

5' - GGAGCGTCATCGACAGGAGC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
aik2	hdac4
aik3	hdac4

Expression

Gene expression in Wild Types + CRISPR1-hdac4

No data available

Phenotype

Phenotype resulting from CRISPR1-hdac4

No data available

Phenotype of all Fish created by or utilizing CRISPR1-hdac4

Phenotype	Fish	Conditions	Figures
female organism viability, abnormal	hdac4^aik2/aik2 (AB)	standard conditions	text only from DeLaurier et al., 2019
ossification premature, abnormal	hdac4^aik2/aik2 (AB)	standard conditions	Fig. 2 from DeLaurier et al., 2019
female organism absent, abnormal	hdac4^aik2/aik2 (AB)	standard conditions	text only from DeLaurier et al., 2019
ceratohyal cartilage ossification premature, abnormal	hdac4^aik2/aik2 (AB)	standard conditions	Fig. 2 from DeLaurier et al., 2019
ceratohyal bone irregularly shaped, abnormal	hdac4^aik2/aik2 (AB)	standard conditions	Fig. 2 from DeLaurier et al., 2019
ceratohyal cartilage postero-medial margin runx2a expression increased amount, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 4 from DeLaurier et al., 2019
ventral mandibular arch lacks parts or has fewer parts of type Meckel's cartilage, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 6 from DeLaurier et al., 2019
ceratohyal cartilage postero-medial margin runx2b expression increased amount, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 4 from DeLaurier et al., 2019
ceratobranchial 2 cartilage ossification premature, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 5 from DeLaurier et al., 2019
neurocranium malformed, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 6 from DeLaurier et al., 2019
ventral hypohyal bone ossification premature, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 5 from DeLaurier et al., 2019
neurocranium morphology, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 6 from DeLaurier et al., 2019
ossification premature, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 2 from DeLaurier et al., 2019
palatoquadrate cartilage anterior region decreased size, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 6 from DeLaurier et al., 2019
ceratohyal cartilage ossification premature, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 5 from DeLaurier et al., 2019
ceratohyal cartilage ossification premature, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 2 from DeLaurier et al., 2019
quadrate decreased size, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 6 from DeLaurier et al., 2019
symplectic ossification premature, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 5 from DeLaurier et al., 2019
quadrate ossification premature, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 5 from DeLaurier et al., 2019
mandibular arch skeleton decreased length, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 6 from DeLaurier et al., 2019
ceratohyal bone irregularly shaped, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 2 from DeLaurier et al., 2019
head decreased length, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 6 from DeLaurier et al., 2019
entopterygoid decreased size, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 6 from DeLaurier et al., 2019
anguloarticular ossification premature, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 5 from DeLaurier et al., 2019
ceratobranchial 1 cartilage ossification premature, abnormal	hdac4^aik3/aik3 (AB)	standard conditions	Fig. 5 from DeLaurier et al., 2019
ventral mandibular arch lacks parts or has fewer parts of type Meckel's cartilage, abnormal	hdac4^aik3/+ (AB)	standard conditions	Fig. 6 from DeLaurier et al., 2019
ossification premature, abnormal	hdac4^aik3/+ (AB)	standard conditions	Fig. 2 from DeLaurier et al., 2019
neurocranium morphology, abnormal	hdac4^aik3/+ (AB)	standard conditions	Fig. 6 from DeLaurier et al., 2019
ventral hypohyal bone ossification premature, abnormal	hdac4^aik3/+ (AB)	standard conditions	Fig. 5 from DeLaurier et al., 2019
ceratohyal cartilage ossification premature, abnormal	hdac4^aik3/+ (AB)	standard conditions	Fig. 2 from DeLaurier et al., 2019
symplectic ossification premature, abnormal	hdac4^aik3/+ (AB)	standard conditions	Fig. 5 from DeLaurier et al., 2019
palatoquadrate cartilage anterior region decreased size, abnormal	hdac4^aik3/+ (AB)	standard conditions	Fig. 6 from DeLaurier et al., 2019
ceratohyal cartilage ossification premature, abnormal	hdac4^aik3/+ (AB)	standard conditions	Fig. 5 from DeLaurier et al., 2019
quadrate decreased size, abnormal	hdac4^aik3/+ (AB)	standard conditions	Fig. 6 from DeLaurier et al., 2019
entopterygoid decreased size, abnormal	hdac4^aik3/+ (AB)	standard conditions	Fig. 6 from DeLaurier et al., 2019
neurocranium hypertrophic, abnormal	hdac4^aik3/+ (AB)	standard conditions	Fig. 6 from DeLaurier et al., 2019
anguloarticular ossification premature, abnormal	hdac4^aik3/+ (AB)	standard conditions	Fig. 5 from DeLaurier et al., 2019

Citations