CRISPR

CRISPR1-kcnj8

ID

ZDB-CRISPR-190304-5

Name

CRISPR1-kcnj8

Previous Names

Kcnj8_p.V65M (1)

Target

kcnj8 (1)

Sequence

5' - GCAGGACGTCTTCACCACTC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
hu11872	kcnj8

Expression

Gene expression in Wild Types + CRISPR1-kcnj8

No data available

Phenotype

Phenotype resulting from CRISPR1-kcnj8

No data available

Phenotype of all Fish created by or utilizing CRISPR1-kcnj8

Phenotype	Fish	Conditions	Figures
heart process process quality, abnormal	kcnj8^{hu11872/hu11872}	standard conditions	Fig. S7 , Fig. S8 from Tessadori et al., 2018
cardiac ventricle increased size, abnormal	kcnj8^{hu11872/hu11872}	standard conditions	Fig. S9 from Tessadori et al., 2018
pericardium edematous, abnormal	kcnj8^{hu11872/hu11872}	standard conditions	Fig. S7 from Tessadori et al., 2018
dorsal aorta blood decreased velocity, abnormal	kcnj8^{hu11872/hu11872}	standard conditions	Fig. S8 from Tessadori et al., 2018
cardiac ventricle increased size, abnormal	kcnj8^hu11872/+	standard conditions	Fig. 2 from Tessadori et al., 2018
posterior cardinal vein blood decreased velocity, abnormal	kcnj8^hu11872/+	standard conditions	Fig. 2 from Tessadori et al., 2018
heart process process quality, abnormal	kcnj8^hu11872/+	standard conditions	Fig. 2 from Tessadori et al., 2018
pericardium edematous, abnormal	kcnj8^hu11872/+	standard conditions	Fig. 2 from Tessadori et al., 2018
dorsal aorta blood decreased velocity, abnormal	kcnj8^hu11872/+	standard conditions	Fig. 2 from Tessadori et al., 2018
basal communicating artery kinked, abnormal	kcnj8^hu11872/+; la116Tg	standard conditions	Fig. S10 from Tessadori et al., 2018
basal communicating artery increased curvature, abnormal	kcnj8^hu11872/+; la116Tg	standard conditions	Fig. S10 from Tessadori et al., 2018
posterior communicating artery increased curvature, abnormal	kcnj8^hu11872/+; la116Tg	standard conditions	Fig. S10 from Tessadori et al., 2018
posterior communicating artery kinked, abnormal	kcnj8^hu11872/+; la116Tg	standard conditions	Fig. S10 from Tessadori et al., 2018
regulation of potassium:proton exchanging ATPase activity decreased process quality, abnormal	kcnj8^{hu11872/hu11872}; p151Tg/p151Tg	primary cell culture: ventricular myocardium	Fig. 4 from Singareddy et al., 2021
regulation of potassium:proton exchanging ATPase activity decreased process quality, abnormal	kcnj8^{hu11872/hu11872}; p151Tg/p151Tg	primary cell culture: bulbus arteriosus	Fig. 6 from Singareddy et al., 2021

Citations