CRISPR

CRISPR1-sqstm1

ID

ZDB-CRISPR-190218-4

Name

CRISPR1-sqstm1

Previous Names

None

Target

sqstm1 (1)

Sequence

5' - GGACCAGGAGGGCTAAAGTG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ibl52	sqstm1

Expression

Gene expression in Wild Types + CRISPR1-sqstm1

No data available

Phenotype

Phenotype resulting from CRISPR1-sqstm1

No data available

Phenotype of all Fish created by or utilizing CRISPR1-sqstm1

Phenotype	Fish	Conditions	Figures
defense response to bacterium decreased efficacy, abnormal	sqstm1^ibl52/ibl52	bacterial treatment by injection: Mycobacterium marinum	Figure 1 , Figure 4 from Xie et al., 2024
defense response to bacterium decreased efficacy, exacerbated	optn^ibl51/ibl51; sqstm1^ibl52/ibl52	bacterial treatment by injection: Mycobacterium marinum	Figure 1 from Xie et al., 2024
defense response to bacterium decreased efficacy, abnormal	optn^ibl51/ibl51; sqstm1^ibl52/ibl52	bacterial treatment by injection: Mycobacterium marinum	Figure 4 from Xie et al., 2024
caudal fin EGFP expression amount, ameliorated	sqstm1^ibl52/ibl52; zf155Tg	chemical treatment by environment: bafilomycin A1	Fig 3 from Zhang et al., 2019
whole organism ab4-sqstm1 labeling decreased amount, abnormal	sqstm1^ibl52/ibl52; zf155Tg	control	Fig. 2 from Zhang et al., 2019
whole organism ab1-map1lc3 labeling amount, ameliorated	sqstm1^ibl52/ibl52; zf155Tg	bacterial treatment by injection: Mycobacterium marinum	Fig 5 from Zhang et al., 2019
whole organism sqstm1 expression decreased amount, abnormal	sqstm1^ibl52/ibl52; zf155Tg	control	Fig. 2 from Zhang et al., 2019
whole organism ab1-map1lc3 labeling amount, ameliorated	sqstm1^ibl52/ibl52; zf155Tg	chemical treatment by environment: bafilomycin A1	Fig 3 from Zhang et al., 2019
defense response to bacterium decreased efficacy, abnormal	sqstm1^ibl52/ibl52; zf155Tg	bacterial treatment by injection: Mycobacterium marinum	Fig. 4 from Zhang et al., 2019
defense response to bacterium decreased efficacy, abnormal	sqstm1^ibl52/ibl52; zf155Tg + MO5-optn	bacterial treatment by injection: Mycobacterium marinum	Fig. 4 from Zhang et al., 2019

Citations