CRISPR

CRISPR4-mmp9

ID

ZDB-CRISPR-190131-4

Name

CRISPR4-mmp9

Previous Names

None

Target

mmp9 (1)

Sequence

5' - TTGATGCCATGAAGCAGCC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
mi5003	mmp9
mi5004	mmp9

Expression

Gene expression in Wild Types + CRISPR4-mmp9

No data available

Phenotype

Phenotype resulting from CRISPR4-mmp9

No data available

Phenotype of all Fish created by or utilizing CRISPR4-mmp9

Phenotype	Fish	Conditions	Figures
retinal rod cell increased amount, abnormal	mmp9^{mi5003/mi5003}	light ablation: photoreceptor cell	Fig. 6 from Silva et al., 2020
retinal rod cell rho expression increased amount, abnormal	mmp9^{mi5003/mi5003}	light ablation: photoreceptor cell	Fig. 8 from Silva et al., 2020
retinal cone cell increased amount, abnormal	mmp9^{mi5003/mi5003}	chemical treatment by environment: dexamethasone, light ablation: photoreceptor cell	Fig. 10 from Silva et al., 2020
retina tnfa expression increased amount, abnormal	mmp9^{mi5003/mi5003}	light ablation: photoreceptor cell	Fig. 7 from Silva et al., 2020
retinal outer nuclear layer cell population proliferation increased occurrence, abnormal	mmp9^{mi5003/mi5003}	light ablation: photoreceptor cell	Fig. 5, Fig. 6 from Silva et al., 2020
retina cell population proliferation increased occurrence, abnormal	mmp9^{mi5003/mi5003}	light ablation: photoreceptor cell	Fig. 5 from Silva et al., 2020
microglial cell retina amount, ameliorated	mmp9^{mi5003/mi5003}	chemical treatment by environment: dexamethasone, light ablation: photoreceptor cell	Fig. 10 from Silva et al., 2020
microglial cell retina increased amount, abnormal	mmp9^{mi5003/mi5003}	light ablation: photoreceptor cell	Fig. 10 from Silva et al., 2020
retina nfkb2 expression increased amount, abnormal	mmp9^{mi5003/mi5003}	light ablation: photoreceptor cell	Fig. 7 from Silva et al., 2020
retinal cone cell increased amount, abnormal	mmp9^{mi5003/mi5003}	light ablation: photoreceptor cell	Fig. 6 from Silva et al., 2020
retina gnat2 expression decreased amount, abnormal	mmp9^{mi5003/mi5003}	light ablation: photoreceptor cell	Fig. 9 from Silva et al., 2020
retina microglial cell ab-4c4 labeling increased amount, abnormal	mmp9^{mi5003/mi5003}	light ablation: photoreceptor cell	Fig. 10 from Silva et al., 2020
retinal cone cell cell population proliferation increased occurrence, abnormal	mmp9^{mi5003/mi5003}	light ablation: photoreceptor cell	Fig. 6 from Silva et al., 2020
retinal rod cell cell population proliferation increased occurrence, abnormal	mmp9^{mi5003/mi5003}	light ablation: photoreceptor cell	Fig. 6 from Silva et al., 2020
retinal cone cell decreased amount, abnormal	mmp9^{mi5003/mi5003}	light ablation: photoreceptor cell	Fig. 9 from Silva et al., 2020
retina tnfa expression increased amount, abnormal	mmp9^{mi5003/mi5003}	standard conditions	Fig. 7 from Silva et al., 2020
retina nfkb1 expression increased amount, abnormal	mmp9^{mi5003/mi5003}	light ablation: photoreceptor cell	Fig. 7 from Silva et al., 2020

Citations