CRISPR

CRISPR1-lhfpl5b

ID

ZDB-CRISPR-180926-1

Name

CRISPR1-lhfpl5b

Previous Names

None

Target

Sequence

5' - CAACCCAATCACCTCGGAAT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
vo35	lhfpl5b

Expression

Gene expression in Wild Types + CRISPR1-lhfpl5b

No data available

Phenotype

Phenotype resulting from CRISPR1-lhfpl5b

No data available

Phenotype of all Fish created by or utilizing CRISPR1-lhfpl5b

Phenotype	Fish	Conditions	Figures
neuromast has fewer parts of type neuromast hair cell, abnormal	lhfpl5b^vo35/vo35	standard conditions	FIGURE 4 from Erickson et al., 2020
lateral line displaced, abnormal	lhfpl5b^vo35/vo35	mechanical stress, ablation: lateral line, chemical treatment by environment: copper(II) sulfate	Figure 2 from Holmgren et al., 2021
thalamus pth2 expression decreased amount, abnormal	lhfpl5b^vo35/vo35	standard conditions	Fig. 1. , Fig. 2. from Venuto et al., 2022
thalamus pth2 expression decreased amount, abnormal	lhfpl5b^vo35/vo35	housing conditions	Fig. 3. from Venuto et al., 2022
lateral line elongated, abnormal	lhfpl5b^vo35/vo35	mechanical stress, ablation: lateral line, chemical treatment by environment: copper(II) sulfate	Figure 2 from Holmgren et al., 2021
thalamus pth2 expression decreased amount, abnormal	lhfpl5b^vo35/vo35	chemical treatment by environment: neomycin, chemical ablation: neuromast hair cell	Fig. 1. from Venuto et al., 2022
neuromast hair cell detection of mechanical stimulus involved in sensory perception of sound decreased occurrence, abnormal	lhfpl5b^vo35/vo35	standard conditions	FIGURE 4 from Erickson et al., 2020
thalamus EGFP expression decreased amount, abnormal	lhfpl5b^vo35/vo35; unb2Tg	standard conditions	Fig. 5. from Venuto et al., 2022
neuromast detection of mechanical stimulus involved in sensory perception of sound occurrence, ameliorated	lhfpl5b^vo35/vo35; vo23Tg	standard conditions	FIGURE 4 from Erickson et al., 2020

Citations