CRISPR

CRISPR1-gja8b

ID

ZDB-CRISPR-180213-345

Name

CRISPR1-gja8b

Previous Names

None

Target

gja8b (1)

Sequence

5' - GGGAAGCGTCCGTACGGCCA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
zko933a	gja8b

Expression

Gene expression in Wild Types + CRISPR1-gja8b

No data available

Phenotype

Phenotype resulting from CRISPR1-gja8b

No data available

Phenotype of all Fish created by or utilizing CRISPR1-gja8b

Phenotype	Fish	Conditions	Figures
lens fiber cell autophagosome decreased amount, abnormal	gja8b^{zko933a/zko933a}	standard conditions	Fig. 3 from Ping et al., 2021
lens fiber cell endoplasmic reticulum disassembly process quality, ameliorated	gja8b^{zko933a/zko933a}	chemical treatment by environment: sirolimus	Fig. 7 from Ping et al., 2021
lens Ab14-hspa5 labeling increased amount, abnormal	gja8b^{zko933a/zko933a}	standard conditions	Fig. 2 , Fig. 7 from Ping et al., 2021
lens central region has extra parts of type lens fiber cell cytoskeleton, abnormal	gja8b^{zko933a/zko933a}	chemical treatment by environment: 3-methyladenine, chemical treatment by environment: sirolimus	Fig. 8 from Ping et al., 2021
lens fiber cell differentiation decreased process quality, abnormal	gja8b^{zko933a/zko933a}	standard conditions	Fig. 2 from Ping et al., 2021
lens zl-1 labeling increased amount, abnormal	gja8b^{zko933a/zko933a}	standard conditions	Fig. 2 from Ping et al., 2021
lens fiber cell organelle disassembly process quality, ameliorated	gja8b^{zko933a/zko933a}	chemical treatment by environment: sirolimus	Fig. 7 from Ping et al., 2021
lens opaque, abnormal	gja8b^{zko933a/zko933a}	standard conditions	Fig. 1 from Ping et al., 2021
lens fiber cell autophagy decreased process quality, abnormal	gja8b^{zko933a/zko933a}	standard conditions	Fig. 3 from Ping et al., 2021
lens Ab14-hspa5 labeling increased amount, abnormal	gja8b^{zko933a/zko933a}	chemical treatment by environment: 3-methyladenine, chemical treatment by environment: sirolimus	Fig. 8 from Ping et al., 2021
lens ab1-mip labeling increased amount, abnormal	gja8b^{zko933a/zko933a}	chemical treatment by environment: 3-methyladenine, chemical treatment by environment: sirolimus	Fig. 8 from Ping et al., 2021
lens development in camera-type eye process quality, ameliorated	gja8b^{zko933a/zko933a}	chemical treatment by environment: sirolimus	Fig. 7 from Ping et al., 2021
lens Ab14-hspa5 labeling amount, ameliorated	gja8b^{zko933a/zko933a}	chemical treatment by environment: sirolimus	Fig. 7 , Fig. 8 from Ping et al., 2021
lens ab1-mip labeling increased amount, abnormal	gja8b^{zko933a/zko933a}	standard conditions	Fig. 2 , Fig. 7 from Ping et al., 2021
lens ab1-mip labeling amount, ameliorated	gja8b^{zko933a/zko933a}	chemical treatment by environment: sirolimus	Fig. 7 , Fig. 8 from Ping et al., 2021
lens development in camera-type eye decreased process quality, abnormal	gja8b^{zko933a/zko933a}	chemical treatment by environment: 3-methyladenine, chemical treatment by environment: sirolimus	Fig. 8 from Ping et al., 2021
lens central region has extra parts of type lens fiber cell nucleus, abnormal	gja8b^{zko933a/zko933a}	standard conditions	Fig. 2 , Fig. 7 from Ping et al., 2021
lens opaque, abnormal	gja8b^{zko933a/zko933a}	chemical treatment by environment: 3-methyladenine, chemical treatment by environment: sirolimus	Fig. 8 from Ping et al., 2021
lens central region has number of lens fiber cell nucleus, ameliorated	gja8b^{zko933a/zko933a}	chemical treatment by environment: sirolimus	Fig. 7 from Ping et al., 2021
lens fiber cell organelle disassembly decreased process quality, abnormal	gja8b^{zko933a/zko933a}	standard conditions	Fig. 2 , Fig. 7 from Ping et al., 2021
lens fiber cell autophagosome amount, ameliorated	gja8b^{zko933a/zko933a}	chemical treatment by environment: sirolimus	Fig. 6 from Ping et al., 2021
lens central region has extra parts of type lens fiber cell nucleus, abnormal	gja8b^{zko933a/zko933a}	chemical treatment by environment: 3-methyladenine, chemical treatment by environment: sirolimus	Fig. 8 from Ping et al., 2021
lens development in camera-type eye decreased process quality, abnormal	gja8b^{zko933a/zko933a}	control	Fig. 7 from Ping et al., 2021
lens central region has number of lens fiber cell endoplasmic reticulum, ameliorated	gja8b^{zko933a/zko933a}	chemical treatment by environment: sirolimus	Fig. 7 from Ping et al., 2021
lens fiber cell endoplasmic reticulum disassembly decreased process quality, abnormal	gja8b^{zko933a/zko933a}	standard conditions	Fig. 2 , Fig. 7 from Ping et al., 2021
lens central region has number of lens fiber cell cytoskeleton, ameliorated	gja8b^{zko933a/zko933a}	chemical treatment by environment: sirolimus	Fig. 7 from Ping et al., 2021
lens central region has extra parts of type lens fiber cell endoplasmic reticulum, abnormal	gja8b^{zko933a/zko933a}	standard conditions	Fig. 2 , Fig. 7 from Ping et al., 2021
lens central region has extra parts of type lens fiber cell cytoskeleton, abnormal	gja8b^{zko933a/zko933a}	standard conditions	Fig. 2 , Fig. 7 from Ping et al., 2021

Citations