CRISPR

CRISPR2-esr1

ID

ZDB-CRISPR-171026-1

Name

CRISPR2-esr1

Previous Names

None

Target

esr1 (1)

Sequence

5' - GCTTCAGTGGGATACTACC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
umo10	esr1

Expression

Gene expression in Wild Types + CRISPR2-esr1

No data available

Phenotype

Phenotype resulting from CRISPR2-esr1

No data available

Phenotype of all Fish created by or utilizing CRISPR2-esr1

Phenotype	Fish	Conditions	Figures
testis esr2a expression decreased amount, abnormal	esr1^umo10/umo10	standard conditions	Fig. 10 from Lu et al., 2017
male organism ratio female organism, abnormal	esr1^umo10/umo10	standard conditions	Fig. 2 from Lu et al., 2017
sex determination process quality, abnormal	esr1^umo10/umo10	standard conditions	Fig. 2 from Lu et al., 2017
female organism decreased amount, abnormal	esr1^umo10/umo10	standard conditions	Fig. 2 from Lu et al., 2017
male organism increased amount, abnormal	esr1^umo10/umo10	standard conditions	Fig. 2 from Lu et al., 2017
ovarian follicle stromal cell hyperplastic, abnormal	esr1^umo10/umo10; esr2a^umo12/umo12	standard conditions	Fig. 3, Fig. 5, Fig. 6, Fig. 7 from Lu et al., 2017
ovarian follicle degenerate, abnormal	esr1^umo10/umo10; esr2a^umo12/umo12	standard conditions	Fig. 6 from Lu et al., 2017
male organism ratio female organism, abnormal	esr1^umo10/umo10; esr2a^umo12/umo12	standard conditions	Fig. 2 from Lu et al., 2017
sex determination process quality, abnormal	esr1^umo10/umo10; esr2a^umo12/umo12	standard conditions	Fig. 2 from Lu et al., 2017
male organism increased amount, abnormal	esr1^umo10/umo10; esr2a^umo12/umo12	standard conditions	Fig. 2 from Lu et al., 2017
female organism decreased amount, abnormal	esr1^umo10/umo10; esr2a^umo12/umo12	standard conditions	Fig. 2 from Lu et al., 2017
male organism ratio female organism, abnormal	esr1^umo10/umo10; esr2b^umo13/umo13	standard conditions	Fig. 2 from Lu et al., 2017
sex determination process quality, abnormal	esr1^umo10/umo10; esr2b^umo13/umo13	standard conditions	Fig. 2 from Lu et al., 2017
female organism decreased amount, abnormal	esr1^umo10/umo10; esr2b^umo13/umo13	standard conditions	Fig. 2 from Lu et al., 2017
male organism increased amount, abnormal	esr1^umo10/umo10; esr2b^umo13/umo13	standard conditions	Fig. 2 from Lu et al., 2017
chorion deformed, abnormal	esr1^umo10; esr2a^umo12	standard conditions	Fig. 8 from Lu et al., 2017
hatching premature, abnormal	esr1^umo10; esr2a^umo12	standard conditions	Fig. 8 from Lu et al., 2017
ovarian follicle stromal cell hyperplastic, abnormal	esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 5 from Lu et al., 2017
male organism ratio female organism, abnormal	esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 2 from Lu et al., 2017
sex determination process quality, abnormal	esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 2 from Lu et al., 2017
female organism absent, abnormal	esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 6, Fig. 7 from Lu et al., 2017
male organism increased amount, abnormal	esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 2 from Lu et al., 2017
female organism decreased amount, abnormal	esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 2 from Lu et al., 2017
regulation of female gonad development disrupted, abnormal	cyp19a1a^umo5/umo5; esr1^umo10/+; esr2a^umo11/umo11; esr2b^umo13/+	chemical treatment by environment: bisphenol A	Fig. 6 from Song et al., 2019
female sex determination decreased occurrence, abnormal	cyp19a1a^umo5/umo5; esr1^umo10/+; esr2a^umo11/umo11; esr2b^umo13/+	chemical treatment by environment: bisphenol A	Fig. 6 from Song et al., 2019
regulation of female gonad development disrupted, abnormal	cyp19a1a^umo5/umo5; esr1^umo10/+; esr2a^umo11/umo11; esr2b^umo13/umo13	chemical treatment by environment: bisphenol A	Fig. 6 from Song et al., 2019
female sex determination absent process, abnormal	cyp19a1a^umo5/umo5; esr1^umo10/+; esr2a^umo11/umo11; esr2b^umo13/umo13	chemical treatment by environment: bisphenol A	Fig. 6 from Song et al., 2019
female sex determination occurrence, ameliorated	cyp19a1a^umo5/umo5; esr1^umo10/umo10; esr2a^umo11/+; esr2b^umo13/umo13	chemical treatment by environment: bisphenol A	Fig. 6 from Song et al., 2019
regulation of female gonad development normal occurrence, ameliorated	cyp19a1a^umo5/umo5; esr1^umo10/umo10; esr2a^umo11/+; esr2b^umo13/umo13	chemical treatment by environment: bisphenol A	Fig. 6 from Song et al., 2019
regulation of female gonad development disrupted, abnormal	cyp19a1a^umo5/umo5; esr1^umo10/umo10; esr2a^umo11/umo11; esr2b^umo13/+	chemical treatment by environment: bisphenol A	Fig. 6 from Song et al., 2019
female sex determination absent process, abnormal	cyp19a1a^umo5/umo5; esr1^umo10/umo10; esr2a^umo11/umo11; esr2b^umo13/+	chemical treatment by environment: bisphenol A	Fig. 6 from Song et al., 2019
regulation of female gonad development disrupted, abnormal	cyp19a1a^umo5/umo5; esr1^umo10/umo10; esr2a^umo11/umo11; esr2b^umo13/umo13	chemical treatment by environment: bisphenol A	Fig. 6 from Song et al., 2019
female sex determination absent process, abnormal	cyp19a1a^umo5/umo5; esr1^umo10/umo10; esr2a^umo11/umo11; esr2b^umo13/umo13	chemical treatment by environment: bisphenol A	Fig. 6 from Song et al., 2019
male organism increased amount, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/+; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/+	standard conditions	Fig. 4 from Wu et al., 2020
male organism ratio female organism, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/+; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/+	standard conditions	Fig. 4 from Wu et al., 2020
female organism decreased amount, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/+; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/+	standard conditions	Fig. 4 from Wu et al., 2020
male organism increased amount, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/+; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
female organism decreased amount, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/+; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
female organism ratio male organism, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/+; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
male organism ratio female organism, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/umo15; esr1^umo10/+; esr2a^umo12/+; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
male organism decreased amount, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/umo15; esr1^umo10/+; esr2a^umo12/+; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
female organism increased amount, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/umo15; esr1^umo10/+; esr2a^umo12/+; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
male organism ratio female organism, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/umo15; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/+	standard conditions	Fig. 4 from Wu et al., 2020
male organism decreased amount, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/umo15; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/+	standard conditions	Fig. 4 from Wu et al., 2020
female organism increased amount, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/umo15; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/+	standard conditions	Fig. 4 from Wu et al., 2020
male organism ratio female organism, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/umo15; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
ovarian follicle degenerate, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/umo15; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
male organism decreased amount, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/umo15; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
female organism increased amount, abnormal	cyp19a1a^umo5/+; dmrt1^umo15/umo15; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
female organism decreased amount, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/+; esr1^umo10/+; esr2a^umo12/+; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
female organism ratio male organism, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/+; esr1^umo10/+; esr2a^umo12/+; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
male organism increased amount, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/+; esr1^umo10/+; esr2a^umo12/+; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
female organism decreased amount, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/+; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/+	standard conditions	Fig. 4 from Wu et al., 2020
female organism ratio male organism, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/+; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/+	standard conditions	Fig. 4 from Wu et al., 2020
male organism increased amount, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/+; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/+	standard conditions	Fig. 4 from Wu et al., 2020
female organism decreased amount, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/+; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
female organism ratio male organism, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/+; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
male organism increased amount, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/+; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
male organism decreased amount, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/umo15; esr1^umo10/+; esr2a^umo12/+; esr2b^umo13/+	standard conditions	Fig. 4 from Wu et al., 2020
male organism ratio female organism, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/umo15; esr1^umo10/+; esr2a^umo12/+; esr2b^umo13/+	standard conditions	Fig. 4 from Wu et al., 2020
female organism increased amount, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/umo15; esr1^umo10/+; esr2a^umo12/+; esr2b^umo13/+	standard conditions	Fig. 4 from Wu et al., 2020
male organism decreased amount, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/umo15; esr1^umo10/+; esr2a^umo12/+; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
male organism ratio female organism, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/umo15; esr1^umo10/+; esr2a^umo12/+; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
female organism increased amount, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/umo15; esr1^umo10/+; esr2a^umo12/+; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
male organism ratio female organism, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/umo15; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/+	standard conditions	Fig. 4 from Wu et al., 2020
male organism decreased amount, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/umo15; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/+	standard conditions	Fig. 4 from Wu et al., 2020
female organism increased amount, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/umo15; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/+	standard conditions	Fig. 4 from Wu et al., 2020
male organism ratio female organism, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/umo15; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
ovarian follicle degenerate, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/umo15; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
male organism decreased amount, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/umo15; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020
female organism increased amount, abnormal	cyp19a1a^umo5/umo5; dmrt1^umo15/umo15; esr1^umo10/umo10; esr2a^umo12/umo12; esr2b^umo13/umo13	standard conditions	Fig. 4 from Wu et al., 2020

Citations