CRISPR

CRISPR1-gnb5a

ID

ZDB-CRISPR-161107-1

Name

CRISPR1-gnb5a

Previous Names

None

Target

gnb5a (1)

Sequence

5' - GGATGCGTTTACCACAAATA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
hu11433	gnb5a

Expression

Gene expression in Wild Types + CRISPR1-gnb5a

No data available

Phenotype

Phenotype resulting from CRISPR1-gnb5a

No data available

Phenotype of all Fish created by or utilizing CRISPR1-gnb5a

Phenotype	Fish	Conditions	Figures
optokinetic behavior disrupted, abnormal	gnb5a^{hu11433/hu11433}; gnb5b^{hu11443/hu11443}	standard conditions	Fig. S8 from Lodder et al., 2016
heart contraction decreased rate, ameliorated	gnb5a^{hu11433/hu11433}; gnb5b^{hu11443/hu11443}	chemical treatment: carbachol, chemical treatment: anti-arrhythmia drug	Fig. 5. from Veerman et al., 2019
heart contraction decreased rate, abnormal	gnb5a^{hu11433/hu11433}; gnb5b^{hu11443/hu11443}	chemical treatment: carbachol	Fig. 2 from Lodder et al., 2016
heart contraction rate, abnormal	gnb5a^{hu11433/hu11433}; gnb5b^{hu11443/hu11443}	control	Fig. 6 from Sala et al., 2017
heart contraction decreased rate, abnormal	gnb5a^{hu11433/hu11433}; gnb5b^{hu11443/hu11443}	chemical treatment: carbachol	Fig. 5. from Veerman et al., 2019
heart contraction process quality, abnormal	gnb5a^{hu11433/hu11433}; gnb5b^{hu11443/hu11443}	control	Fig. 6 from Sala et al., 2017
thigmotaxis disrupted, abnormal	gnb5a^{hu11433/hu11433}; gnb5b^{hu11443/hu11443}	standard conditions	Fig. 3 from Lodder et al., 2016
swimming behavior process quality, abnormal	gnb5a^{hu11433/hu11433}; gnb5b^{hu11443/hu11443}	standard conditions	Fig. 3 from Lodder et al., 2016
heart contraction process quality, exacerbated	gnb5a^{hu11433/hu11433}; gnb5b^{hu11443/hu11443}	chemical treatment: carbachol	Fig. 6 from Sala et al., 2017
heart contraction increased rate, abnormal	gnb5a^{hu11433/hu11433}; gnb5b^{hu11443/hu11443}	chemical treatment: isoprenaline	Fig. 2 from Lodder et al., 2016

Citations