CRISPR

CRISPR1-ctbp2l

ID

ZDB-CRISPR-160822-1

Name

CRISPR1-ctbp2l

Previous Names

CRISPR1-ctb2b
CRISPR1-ctbp2b

Target

ctbp2l (1)

Sequence

5' - GGCCGGCTGACAGGACTCCA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ya401	ctbp2l

Expression

Gene expression in Wild Types + CRISPR1-ctbp2l

No data available

Phenotype

Phenotype resulting from CRISPR1-ctbp2l

No data available

Phenotype of all Fish created by or utilizing CRISPR1-ctbp2l

Phenotype	Fish	Conditions	Figures
neuromast hair cell cacna1da expression mislocalised, abnormal	ctbp2a^ya400/ya400; ctbp2l^ya401/ya401	standard conditions	Fig. 5 from Lv et al., 2016
neuromast hair cell ribbon synapse mislocalised, abnormal	ctbp2a^ya400/ya400; ctbp2l^ya401/ya401	standard conditions	Fig. 3 , Fig. 5 from Lv et al., 2016
retinal outer plexiform layer ribbon synapse composition, abnormal	ctbp2a^ya400/ya400; ctbp2l^ya401/ya401	standard conditions	Fig. 3 from Lv et al., 2016
neuromast hair cell ribbon synapse ab1-ctbp labeling decreased amount, abnormal	ctbp2a^ya400/ya400; ctbp2l^ya401/ya401	standard conditions	Fig. 2 from Lv et al., 2016
neuromast hair cell ribbon synapse ctbp2a expression mislocalised, abnormal	ctbp2a^ya400/ya400; ctbp2l^ya401/ya401	standard conditions	Fig. 2 from Lv et al., 2016
neuromast hair cell voltage-gated calcium channel complex mislocalised, abnormal	ctbp2a^ya400/ya400; ctbp2l^ya401/ya401	standard conditions	Fig. 5 from Lv et al., 2016
neuromast hair cell presynapse assembly decreased process quality, abnormal	ctbp2a^ya400/ya400; ctbp2l^ya401/ya401	standard conditions	Fig. 3 , Fig. 5 from Lv et al., 2016
neuromast hair cell ribbon synapse ctbp2l expression absent, abnormal	ctbp2a^ya400/ya400; ctbp2l^ya401/ya401	standard conditions	Fig. 2 from Lv et al., 2016
neuromast hair cell ribbon synapse decreased volume, abnormal	ctbp2a^ya400/ya400; ctbp2l^ya401/ya401	standard conditions	Fig. 3 from Lv et al., 2016
neuromast hair cell calcium channel activity increased occurrence, abnormal	ctbp2a^ya400/ya400; ctbp2l^ya401/ya401	standard conditions	Fig. 4 from Lv et al., 2016
neuromast postsynaptic density ab1-pan-maguk labeling decreased amount, abnormal	ctbp2a^ya400/ya400; ctbp2l^ya401/ya401	standard conditions	Fig. 2 from Lv et al., 2016
neuromast hair cell ribbon synapse ctbp2a expression decreased amount, abnormal	ctbp2a^ya400/ya400; ctbp2l^ya401/ya401	standard conditions	Fig. 2 from Lv et al., 2016

Citations