CRISPR

CRISPR1-sirt7

ID

ZDB-CRISPR-160525-16

Name

CRISPR1-sirt7

Previous Names

None

Target

sirt7 (1)

Sequence

5' - TCGTCGGCTCAGCTCCTGCA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ihblqs4	sirt7
ihblqs7	sirt7

Expression

Gene expression in Wild Types + CRISPR1-sirt7

No data available

Phenotype

Phenotype resulting from CRISPR1-sirt7

No data available

Phenotype of all Fish created by or utilizing CRISPR1-sirt7

Phenotype	Fish	Conditions	Figures
whole organism vegfaa expression increased amount, abnormal	sirt7^{ihblqs4/ihblqs4}	hypoxia	Figure 2 from Liao et al., 2023
whole organism serpine1 expression increased amount, abnormal	sirt7^{ihblqs4/ihblqs4}	hypoxia	Figure 2 from Liao et al., 2023
response to hypoxia increased magnitude, ameliorated	sirt7^{ihblqs4/ihblqs4}	hypoxia	Figure 2 from Liao et al., 2023
whole organism epoa expression increased amount, abnormal	sirt7^{ihblqs4/ihblqs4}	hypoxia	Figure 2 from Liao et al., 2023
whole organism egln3 expression increased amount, abnormal	sirt7^{ihblqs4/ihblqs4}	hypoxia	Figure 2 from Liao et al., 2023
whole organism cited2 expression increased amount, abnormal	sirt7^{ihblqs4/ihblqs4}	hypoxia	Figure 2 from Liao et al., 2023
nucleate erythrocyte increased amount, exacerbated	sirt7^{ihblqs4/ihblqs4}	hypoxia	Figure 2 from Liao et al., 2023
whole organism viability, ameliorated	sirt7^{ihblqs4/ihblqs4}	hypoxia	Figure 2 from Liao et al., 2023
whole organism hif1aa expression increased amount, abnormal	sirt7^{ihblqs4/ihblqs4}	hypoxia	Figure 7 from Liao et al., 2023
whole organism serpine1 expression increased amount, abnormal	sirt7^{ihblqs7/ihblqs7}	hypoxia	Figure 3 from Liao et al., 2023
nucleate erythrocyte increased amount, exacerbated	sirt7^{ihblqs7/ihblqs7}	hypoxia	Figure 3 from Liao et al., 2023
whole organism hif1aa expression increased amount, abnormal	sirt7^{ihblqs7/ihblqs7}	hypoxia	Figure 7 from Liao et al., 2023
whole organism cited2 expression increased amount, abnormal	sirt7^{ihblqs7/ihblqs7}	hypoxia	Figure 3 from Liao et al., 2023
whole organism pkz expression increased amount, abnormal	sirt7^{ihblqs7/ihblqs7}	viral treatment: Sprivivirus cyprinus	Fig. 4 from Liao et al., 2021
whole organism vegfaa expression increased amount, abnormal	sirt7^{ihblqs7/ihblqs7}	hypoxia	Figure 3 from Liao et al., 2023
whole organism mxc expression increased amount, abnormal	sirt7^{ihblqs7/ihblqs7}	viral treatment: Sprivivirus cyprinus	Fig. 4 from Liao et al., 2021
response to hypoxia increased magnitude, ameliorated	sirt7^{ihblqs7/ihblqs7}	hypoxia	Figure 3 from Liao et al., 2023
whole organism epoa expression increased amount, abnormal	sirt7^{ihblqs7/ihblqs7}	hypoxia	Figure 3 from Liao et al., 2023
whole organism egln3 expression increased amount, abnormal	sirt7^{ihblqs7/ihblqs7}	hypoxia	Figure 3 from Liao et al., 2023
whole organism semi-viable, ameliorated	sirt7^{ihblqs7/ihblqs7}	viral treatment: Sprivivirus cyprinus	Fig. 1, Fig. 4 from Liao et al., 2021
whole organism lta expression increased amount, abnormal	sirt7^{ihblqs7/ihblqs7}	viral treatment: Sprivivirus cyprinus	Fig. 4 from Liao et al., 2021
whole organism viability, ameliorated	sirt7^{ihblqs7/ihblqs7}	hypoxia	Figure 3 from Liao et al., 2023
whole organism ifnphi1 expression increased amount, abnormal	sirt7^{ihblqs7/ihblqs7}	viral treatment: Sprivivirus cyprinus	Fig. 4 from Liao et al., 2021

Citations