Gene
sirt7
- ID
- ZDB-GENE-050208-612
- Name
- sirtuin 7
- Symbol
- sirt7 Nomenclature History
- Previous Names
-
- si:ch211-258l4.6 (1)
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable NAD+ binding activity; histone H3K18 deacetylase activity, NAD-dependent; and hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. Acts upstream of or within antiviral innate immune response and hematopoietic progenitor cell differentiation. Predicted to be active in chromatin and nucleus. Is expressed in retina. Orthologous to human SIRT7 (sirtuin 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu987 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Huang et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | DHS-like NAD/FAD-binding domain superfamily | NAD-dependent sirtuin protein deacylases | Sirtuin family | Sirtuin family, catalytic core domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A2R8QUG9
|
405 |
Interactions and Pathways
No data available
Plasmids
No data available