FIGURE SUMMARY
- Title
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Programmable base editing of zebrafish genome using a modified CRISPR-Cas9 system
- Authors
- Zhang, Y., Qin, W., Lu, X., Xu, J., Huang, H., Bai, H., Li, S., Lin, S.
- Source
- Full text @ Nat. Commun.
Induction of amino-acid change at the tyr site in zebrafish. a The diagram of mutation of human OCA. b Sequencing results at the tyr target. c Amino-acid change at the tyr site. d Phenotypes of the injected tyr +/− zebrafish. Red arrows indicate the overlapped peaks. The substituted base and amino acid are marked with red and yellow, respectively. Red arrowhead indicates the deficient eye |
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Full text @ Nat. Commun.