Fig. 4

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Fig. 6

Expression of lrrc8aa and effect of lrrc8aa knockdown during zebrafish embryogenesis. (A) Relative expression of lrrc8aa during various stages of embryonic development. Values are means ± SE (n = 3). *P < 0.002 compared to 1000cell stage. (B) Brightfield micrographs of 48 hpf larvae developing from onecell stage embryos injected with 1 mmol/L control MO or 0.1-1 mmol/L lrrc8aa ATG MO. Asterisk and arrows show larvae with moderate and severe phenoptypes, respectively. (C) Penetrance of larval phenotypes. Values are means ± SE (n = 3 independent experiments with 185-232 animals).

EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage Range: 1k-cell to Long-pec
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Long-pec
Acknowledgments
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