Expression studies of optn in zebrafish embryos. In situ hybridization using wild-type embryos at 24, 48, and 120 hpf is shown. ase, anterior segment of the eye; b, brain; e, eye; i, developing iris; sm, skeletal muscles; pom, periocular mesenchyme.

ccdc3a (A) and ccdc3b (B) in situ hybridization in zebrafish embryos at 18-, 24-, 48-, 72-, and 120-hpf. ase, anterior segment of the eye; b, brain; e, eye; hv, hyaloid vasculature; oc, oral cavity; pa, pharyngeal arches; s, somites; sm, skeletal muscles.

Acknowledgments
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