- Title
-
An integrated approach for the systematic identification and characterization of heart-enriched genes with unknown functions
- Authors
- Uchida, S., Schneider, A., Wiesnet, M., Jungblut, B., Zarjitskaya, P., Jenniches, K., Kreymborg, K.G., Seeger, W., and Braun, T.
- Source
- Full text @ BMC Genomics
Loss-of-function phenotypes after morpholino injections. (A) Effect of zLrrc39 at 108 hpf and (B) zKlhl31 morpholino injections on zebrafish development at 48 hpf, respectively. Lateral views of non-injected control (upper) and morphant (lower) embryos (Tg(myl7:EGFP-HRAS)s883) are shown. The arrow in (A) indicates the pericardial edema in injected zLrrc39 morphant embryos. (C-E) Fluorescent images of heart sections at 48 hpf of control (C), zLrrc39 (D) and zKlhl31 (E) morphants are shown. Cardiomyocytes of zebrafish embryos were marked by expression of EGFP to delineate cellular morphology. Scale bar: 50 μm. |