Expression of sncga. sncga is not expressed at early developmental stages but is expressed in the nervous system beginning at 26 hours postfertilization (hpf). A: At 26 hpf, lateral view, arrowhead indicates epiphysis; arrows indicate spinal cord neurons. B: At 38 hpf, lateral view, arrowhead point to epiphysis; *indicates hindbrain neurons. C: At 38 hpf, dorsal view, *indicates hindbrain neurons. D: At 2 days postfertilization (dpf), lateral view, arrow indicates cranial ganglia. E: At 2 dpf, dorsal view, arrows indicate cranial ganglia. F: At 3 dpf, dorsal view. G: At 3 dpf, lateral view.

Expression of sncgb. A: sncgb expression initiates earlier than sncga (beginning at the 13-somite stage), but its expression is restricted to the notochord throughout embryogenesis. B: At the 14-somite stage. C: At the 16-somite stage. D: At the 18-somite stage. E: At the 20-somite stage. F: At the 25-somite stage. G: At 1 day postfertilization (dpf), cross-section shown as inset. nt, neural tube; nc, notochord. H: By 48 dpf, sncgb expression begins to diminish. hpf, hours postfertilization; dpf, days postfertilization.

Expression of sncb. sncb expression comes on the earliest of the three synuclein genes, beginning at the eight-somite stage. A: At the 10-somite stage. B: At the 13-somite stage, arrows indicate trigeminal placode. C: At the 14-somite stage, lateral view. D: At the 14-somite stage, dorsal view, arrows indicate trigeminal placode. E: At the 16-somite stage. F: At the 20-somite stage. G: At the 22-somite stage. H: At the 25-somite stage. vd, ventral diencephalon; vt, ventral tegmentum; op, olfactory placode. I: A the 25-somite stage. cg, cranial ganglia. J: At 45 hours postfertilization (hpf), lateral view. K: At 45 hpf, dorsal view. L: At 2 days postfertilization (dpf). M: At 3 dpf, lateral view. N: At 3 dpf, dorsal view.