FIGURE SUMMARY
Title

Inhibition of Jagged-mediated Notch signaling disrupts zebrafish biliary development and generates multi-organ defects compatible with an Alagille syndrome phenocopy

Authors
Lorent, K., Yeo, S.Y., Oda, T., Chandrasekharappa, S., Chitnis, A., Matthews, R.P., and Pack, M.
Source
Full text @ Development
Fig. 5

Liver expression of zebrafish jagged and notch genes. (A-C) Lateral view of wild-type 72-hpf larvae processed for RNA in situ hybridization using jagged 1 (A), jagged 2 (B) and jagged 3 (C) antisense probes. All three jagged genes are expressed in the larval liver (arrow), but jagged 2 expression is most pronounced. Expression in the branchial arches is also evident. (D-G) Lateral view of wild-type 72-hpf larvae processed for RNA in situ hybridization using notch 1a (D), notch 1b (E), notch 2 (F) and notch 5 (G) probes. All notch genes are expressed in the developing larval liver and the branchial arches.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development
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