Person

Juan, Thomas

Person ID
ZDB-PERS-181016-5
Email
thomas.Juan@igp.uu.se
URL
Affiliation
Stainier Lab
Address
Uppsala University Department of Immunology, Genetics and Pathology Rudbecklaboratoriet, Dag Hammarskjölds Väg 20, 752 37 Uppsala, Sweden
Country
Sweden
Phone
Fax
ORCID ID
0000-0002-9654-3717
Biography and Research Interest
I investigate blood flow mechanosensation during cardiovascular system development. I implement and optimize state-of-the-art genetic tools to zebrafish, such as degron or ribozyme-mediated knockdown strategies. In addition, I am passionate about streamlining research processes by automating routine tasks and developing user-friendly bench software to assist my lab members.
Publications
Non-Zebrafish Publications
Xie L, Jakutis G, Dooley CM, Guenther S, Kontarakis Z, Howard S, Juan T, Stainier DYR. Induction of a transcriptional adaptation response by RNA destabilization events. EMBO Reports, 2025, DOI: doi: 10.1038/s44319-025-00427-3

Falcucci L, Dooley CM, Adamoski D, Juan T, Martinez J, Georgieva AM, Mamchaoui K, Cirzi C, Stainier DYR. Transcriptional adaptation drives utrophin 1 upregulation in Duchenne muscular dystrophy. Nature, 2025, DOI: 10.1038/s41586-024-08539-x

Juan T, Ebnicher G. Shh signaling activity predicts cardiac laterality in Astyanax mexicanus populations. Development, In preprints; short article, 2024, DOI: 10.1242/dev.202806

Juan T & Furthauer M. Biology and function of ESCRT-dependent extracellular vesicles. Semin Cell Dev Biol (Review), 2017, DOI: 10.1016/j.semcdb.2017.08.022

Van De Bor V, Zimniak G, Papone L, Cerezo D, Malbouyres M, Juan T, Ruggiero F & Noselli S. Companion blood cells control ovarian stem cell niche microenvironment and homeostasis. Cell Report, 2015, DOI: 10.1016/j.celrep.2015.09.008