Company
Gene Tools, LLC
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Products and Services
Morpholino Antisense Oligos
We supply the developmental biology research community with Morpholino antisense oligos. Morpholinos are used to knock down gene expression and block pre-mRNA splicing events (see the key zebrafish references below). Morpholinos are superior for microinjection over other antisense structural types as they are non-toxic in embryos, have predictable targeting and excellent sequence specificity with minimal non-antisense activity. Gene Tools provides a free Morpholino oligo design service for its customers. Contact us for details.
PUBLICATIONS:
Draper B.W., PA Morcos, and CB Kimmel. (2001) Inhibition of Zebrafish fgf8 pre-mRNA splicing with morpholino oligos: a quantifiable method for gene knockdown. Genesis 30:154-156
Review Article
James Summerton. Morpholino antisense oligomers: the case for an RNase H-independent structural type. Biochemica et Biophysica Acta 1489 (1999)141-158
Review Article
James Summerton and Dwight Weller. Morpholino Antisense Oligomers: Design, Preparation and Properties. Antisense and Nucleic Acid Drug Development 7 (1997) 187-195
Partridge M, Vincent A, Matthews P, Puma J, Stein D, Summerton J. A simple method for delivering morpholino antisense oligos into the cytoplasm of cells. Antisense Nucleic Acid Drug Dev. 1996 Fall;6(3):169-75.
We supply the developmental biology research community with Morpholino antisense oligos. Morpholinos are used to knock down gene expression and block pre-mRNA splicing events (see the key zebrafish references below). Morpholinos are superior for microinjection over other antisense structural types as they are non-toxic in embryos, have predictable targeting and excellent sequence specificity with minimal non-antisense activity. Gene Tools provides a free Morpholino oligo design service for its customers. Contact us for details.
PUBLICATIONS:
Draper B.W., PA Morcos, and CB Kimmel. (2001) Inhibition of Zebrafish fgf8 pre-mRNA splicing with morpholino oligos: a quantifiable method for gene knockdown. Genesis 30:154-156
Review Article
James Summerton. Morpholino antisense oligomers: the case for an RNase H-independent structural type. Biochemica et Biophysica Acta 1489 (1999)141-158
Review Article
James Summerton and Dwight Weller. Morpholino Antisense Oligomers: Design, Preparation and Properties. Antisense and Nucleic Acid Drug Development 7 (1997) 187-195
Partridge M, Vincent A, Matthews P, Puma J, Stein D, Summerton J. A simple method for delivering morpholino antisense oligos into the cytoplasm of cells. Antisense Nucleic Acid Drug Dev. 1996 Fall;6(3):169-75.
Company Representative
| Moulton, Jon D. Executive | Jiang, Shan | Nagamine, Brandy Technical |