| Phenotype: | pharyngeal arch neural crest cell disorganized, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | pharyngeal arch |
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| Synonyms: | pharyngeal arches |
| Definition: | One of a series of paired bony or cartilaginous arches that develop along the lateral walls of the foregut. The pharyngeal arches have developmental contributions from endoderm, mesoderm, and neural crest cells and are separated by anterior lateral endoderm out-pockets known as pharyngeal pouches. There are seven pharyngeal arches. |
| Ontology: | Anatomy Ontology [ZFA:0001306] |
| Name: | neural crest cell |
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| Synonyms: | neural crest cells |
| Definition: | A cell of the neural crest. The neural crest is a strip of specialized ectoderm, the neural plate border, which flanks each side of the embryonic neural plate. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesenchymal transition and delamination to form migratory neural crest cells. Most of the cranial and all of the spinal sensory ganglion cells arise by differentiation of neural crest cells. |
| Ontology: | Anatomy Ontology [ZFA:0009165] |
| Name: | disorganized |
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| Synonyms: | |
| Definition: | A structural quality inhering in a bearer by virtue of the bearer's lacking organisation. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000937] |