| Phenotype: | microglial cell lysosome decreased functionality, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | microglial cell |
|---|---|
| Synonyms: | microglia |
| Definition: | A central nervous system macrophage found in the parenchyma of the central nervous system. |
| Ontology: | Anatomy Ontology [ZFA:0009077] |
| Name: | lysosome |
|---|---|
| Synonyms: | |
| Definition: | A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. |
| Ontology: | GO: Cellular Component [GO:0005764] QuickGO AmiGO |
| Name: | decreased functionality |
|---|---|
| Synonyms: | dysfunction, dysfunctional, having decreased function, impaired, lacks function of type, low functionality, partial functionality |
| Definition: | A functionality quality held by the bearer when the latter exhibits decreased ability to perform a regular function(s). |
| Ontology: | Phenotypic Quality Ontology [PATO:0001624] |