| Phenotype: | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay increased process quality, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
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| Synonyms: | mRNA breakdown, nonsense-mediated decay, mRNA catabolic process, nonsense-mediated, mRNA catabolism, nonsense-mediated, mRNA degradation, nonsense-mediated decay, nonsense-mediated mRNA decay, nuclear mRNA catabolic process, nonsense-mediated decay |
| Definition: | The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. |
| Ontology: | GO: Biological Process [GO:0000184] QuickGO AmiGO |
| Name: | increased process quality |
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| Synonyms: | |
| Definition: | A quality of a process that has a value that is increased compared to normal or average. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002304] |