| Phenotype: | Kupffer's vesicle vacuole increased volume, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | Kupffer's vesicle |
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| Synonyms: | ciliated organ of asymmetry |
| Definition: | Small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period. Kupffer's vesicle has been compared to the mouse embryonic node. |
| Ontology: | Anatomy Ontology [ZFA:0000001] |
| Name: | vacuole |
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| Synonyms: | vacuolar carboxypeptidase Y |
| Definition: | A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. |
| Ontology: | GO: Cellular Component [GO:0005773] QuickGO AmiGO |
| Name: | increased volume |
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| Synonyms: | high volume, large volume |
| Definition: | A volume which is relatively high. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000595] |