| Phenotype: | astrocyte regulation of glutamate uptake involved in transmission of nerve impulse decreased process quality, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | astrocyte |
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| Synonyms: | astrocytes |
| Definition: | A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. |
| Ontology: | Anatomy Ontology [ZFA:0009075] |
| Name: | regulation of glutamate uptake involved in transmission of nerve impulse |
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| Synonyms: | regulation of glutamate reuptake, regulation of glutamate uptake during transmission of nerve impulse, regulation of glutamate uptake involved in conduction of nerve impulse, regulation of L-glutamate reuptake, regulation of L-glutamate uptake during transmission of nerve impulse |
| Definition: | Any process that modulates the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell. |
| Ontology: | GO: Biological Process [GO:0051946] QuickGO AmiGO |
| Name: | decreased process quality |
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| Synonyms: | |
| Definition: | A quality of a process that has a value that is decreased compared to normal or average. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002302] |