| Phenotype: | caudal hematopoietic tissue hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal |
|---|---|
| Note: | This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality. |
EXPRESSION ANATOMY:
| Name: | caudal hematopoietic tissue |
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| Synonyms: | |
| Definition: | Tissue that lies between the caudal artery and the caudal vein plexus where definitive hematopoiesis occurs after 48hpf and before the hematopoietic progenitors migrate to the thymus and kidney. |
| Ontology: | Anatomy Ontology [ZFA:0005898] |
| Name: | hematopoietic multipotent progenitor cell |
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| Synonyms: | hemopoietic progenitor cell |
| Definition: | A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans. |
| Ontology: | Anatomy Ontology [ZFA:0009354] |
EXPRESSED GENE:
| Symbol: | runx1 | ||||||||||||
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| Name: | RUNX family transcription factor 1 | ||||||||||||
| Previous Names: | runx1a (1), runxa, aml1 (1) | ||||||||||||
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| Location: | Chr: 1 Mapping Details/Browsers | ||||||||||||
EXPRESSION QUALITY:
| Name: | decreased amount |
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| Synonyms: | decreased, decreased number, present in fewer numbers in organism, reduced, subnumerary |
| Definition: | An amount which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001997] |