| Phenotype: | thymus hematopoietic stem cell migration decreased occurrence, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | thymus |
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| Synonyms: | |
| Definition: | Paired organ where maturation of T-lymphocytes occurs. The adult thymus located on the dorsomedial aspect of the branchial cavity above the third pharyngeal cartilage. The thymus undergoes a period of rapid growth beginning at about the third week and continuing for several more weeks. Accompanying this growth is a dramatic change in the shape of the thymus. It is ovoid initially and then starts to grow dorsally along the skull, forming a characteristic protrusion. During this growth period the adult pattern of rag1-positive cortex and rag1-negative medulla becomes established. The protrusions diminish with age and the thymus gradually shrinks; at two years, the thymus is again confined to the pharynx with minimal if any protrusion. |
| Ontology: | Anatomy Ontology [ZFA:0001078] |
| Name: | hematopoietic stem cell migration |
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| Synonyms: | hemopoietic stem cell migration |
| Definition: | The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. |
| Ontology: | GO: Biological Process [GO:0035701] QuickGO AmiGO |
| Name: | decreased occurrence |
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| Synonyms: | decreased incidence |
| Definition: | An occurrence which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002052] |