| Phenotype: | retinal outer plexiform layer synapse disorganized, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | retinal outer plexiform layer |
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| Synonyms: | retinal outer plexiform layers |
| Definition: | The layer within the retina where the bipolar cells synapse with the photoreceptor cells. |
| Ontology: | Anatomy Ontology [ZFA:0001330] |
| Name: | synapse |
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| Synonyms: | electrotonic synapse, mixed synapse, synaptic junction |
| Definition: | The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. |
| Ontology: | GO: Cellular Component [GO:0045202] QuickGO AmiGO |
| Name: | disorganized |
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| Synonyms: | |
| Definition: | A structural quality inhering in a bearer by virtue of the bearer's lacking organisation. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000937] |