| Phenotype: | Kupffer's vesicle motile cilium lacks parts or has fewer parts of type Kupffer's vesicle axonemal central pair, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | Kupffer's vesicle |
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| Synonyms: | ciliated organ of asymmetry |
| Definition: | Small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period. Kupffer's vesicle has been compared to the mouse embryonic node. |
| Ontology: | Anatomy Ontology [ZFA:0000001] |
| Name: | motile cilium |
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| Synonyms: | microtubule-based flagellum, motile cilia, motile primary cilia, motile primary cilium, motile secondary cilium, nodal cilium |
| Definition: | A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell. |
| Ontology: | GO: Cellular Component [GO:0031514] QuickGO AmiGO |
| Name: | lacks parts or has fewer parts of type |
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| Synonyms: | loss of |
| Definition: | The bearer of this quality has_part < n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly. This case includes the limit case, where the bearer lacks all parts of the specified type. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001999] |
| Name: | axonemal central pair |
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| Synonyms: | axonemal microtubule central pair, axoneme central pair, axoneme microtubule central pair, central pair, central-pair microtubules |
| Definition: | Part of the axoneme consisting of the inner two microtubule doublets of the 9+2 axoneme occurring in most motile cilia. |
| Ontology: | GO: Cellular Component [GO:0097540] QuickGO AmiGO |