| Phenotype: | thymus leukocyte EGFP expression decreased distribution, abnormal |
|---|---|
| Note: | This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality. |
EXPRESSION ANATOMY:
| Name: | thymus |
|---|---|
| Synonyms: | |
| Definition: | Paired organ where maturation of T-lymphocytes occurs. The adult thymus located on the dorsomedial aspect of the branchial cavity above the third pharyngeal cartilage. The thymus undergoes a period of rapid growth beginning at about the third week and continuing for several more weeks. Accompanying this growth is a dramatic change in the shape of the thymus. It is ovoid initially and then starts to grow dorsally along the skull, forming a characteristic protrusion. During this growth period the adult pattern of rag1-positive cortex and rag1-negative medulla becomes established. The protrusions diminish with age and the thymus gradually shrinks; at two years, the thymus is again confined to the pharynx with minimal if any protrusion. |
| Ontology: | Anatomy Ontology [ZFA:0001078] |
| Name: | leukocyte |
|---|---|
| Synonyms: | immune cell, leucocyte, white blood cell |
| Definition: | An achromatic cell of the myeloid or lymphoid lineages, found in blood or other tissue. |
| Ontology: | Anatomy Ontology [ZFA:0009309] |
EXPRESSED GENE:
EXPRESSION QUALITY:
| Name: | decreased distribution |
|---|---|
| Synonyms: | low distribution |
| Definition: | A distribution which is relatively low. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001672] |