| Phenotype: | retina adherens junction increased size, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | retina |
|---|---|
| Synonyms: | retinas |
| Definition: | Multi-tissue structure that contains the retinal neural layer and the retinal pigmented epithelium, and develops from the optic cup. |
| Ontology: | Anatomy Ontology [ZFA:0000152] |
| Name: | adherens junction |
|---|---|
| Synonyms: | cell-cell adherens junction |
| Definition: | A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules. |
| Ontology: | GO: Cellular Component [GO:0005912] QuickGO AmiGO |
| Name: | increased size |
|---|---|
| Synonyms: | big, enlarged, great, large |
| Definition: | A size quality which is relatively high. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000586] |