| Phenotype: | macrophage lysosome accumulation macrophage, abnormal |
|---|---|
| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | macrophage |
|---|---|
| Synonyms: | histiocyte |
| Definition: | A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. |
| Ontology: | Anatomy Ontology [ZFA:0009141] |
| Name: | lysosome |
|---|---|
| Synonyms: | |
| Definition: | A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. |
| Ontology: | GO: Cellular Component [GO:0005764] QuickGO AmiGO |
| Name: | accumulation |
|---|---|
| Synonyms: | pooled |
| Definition: | A structural quality of the collection or massing of one physical object within another physical object. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002269] |