| Phenotype: | hindbrain regulation of blood-brain barrier permeability disrupted, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | hindbrain |
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| Synonyms: | rhombencephalon |
| Definition: | The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata and thus these are not distinguished here. From Neuroanatomy of the Zebrafish Brain. |
| Ontology: | Anatomy Ontology [ZFA:0000029] |
| Name: | regulation of blood-brain barrier permeability |
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| Synonyms: | regulation of BBB permeability, regulation of blood/brain barrier permeability |
| Definition: | Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain. |
| Ontology: | GO: Biological Process [GO:1905603] QuickGO AmiGO |
| Name: | disrupted |
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| Synonyms: | |
| Definition: | A quality of a single process inhering in a bearer by virtue of the bearer's being interrupted of its normal course. |
| Ontology: | Phenotypic Quality Ontology [PATO:0001507] |