Phenotype: | ventricular myocardium bicellular tight junction ab1-tjp1 labeling spatial pattern, abnormal |
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Note: | This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality. |
EXPRESSION ANATOMY:
Name: | ventricular myocardium |
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Synonyms: | |
Definition: | Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer. |
Ontology: | Anatomy Ontology [ZFA:0005061] |
Name: | bicellular tight junction |
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Synonyms: | zonula occludens |
Definition: | An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes. |
Ontology: | GO: Cellular Component [GO:0005923] QuickGO AmiGO |
ANTIBODY LABELING:
EXPRESSION QUALITY:
Name: | spatial pattern |
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Synonyms: | distribution, pattern |
Definition: | A spatial quality inhering in a bearer by virtue of the bearer's exhibiting repetition of placement of its parts. |
Ontology: | Phenotypic Quality Ontology [PATO:0000060] |