Phenotype: thymus lymphoid progenitor cell decreased amount, abnormal
Note: This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name.
Name: thymus
Synonyms:
Definition: Paired organ where maturation of T-lymphocytes occurs. The adult thymus located on the dorsomedial aspect of the branchial cavity above the third pharyngeal cartilage. The thymus undergoes a period of rapid growth beginning at about the third week and continuing for several more weeks. Accompanying this growth is a dramatic change in the shape of the thymus. It is ovoid initially and then starts to grow dorsally along the skull, forming a characteristic protrusion. During this growth period the adult pattern of rag1-positive cortex and rag1-negative medulla becomes established. The protrusions diminish with age and the thymus gradually shrinks; at two years, the thymus is again confined to the pharynx with minimal if any protrusion.
Ontology: Anatomy Ontology [ZFA:0001078]
Name: lymphoid progenitor cell
Synonyms: lymphoid progenitor cells
Definition: A progenitor cell restricted to the lymphoid lineage.
Ontology: Anatomy Ontology [ZFA:0009355]
Name: decreased amount
Synonyms: decreased, decreased number, present in fewer numbers in organism, reduced, subnumerary
Definition: An amount which is relatively low.
Ontology: Phenotypic Quality Ontology [PATO:0001997]