cranial neural crest

Term ID

UBERON:0003099

Synonyms

• cephalic neural crest
• CNC
• cranial NCC population
• crista neuralis cranialis
• head crest
• head NCC population
• head neural crest

Definition

neural crest cells (NCCs) originating in the anterior part of the developing embryo and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage. anna

References

• AAO:0010580
• EFO:0003645
• EHDAA2:0004420
• EMAPA:16091
• TAO:0001194
• VHOG:0000063
• XAO:0001001
• ZFA:0001194
• http://en.wikipedia.org/wiki/Cranial_neural_crest

Ontology

Cell Ontology