amylin receptor 3 signaling pathway

Term ID

GO:0150061

Synonyms

• AMY3 signaling pathway

Definition

The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 3 (AMY3), a G protein-coupled receptor complex, on the surface of the target cell. The AMY3 signaling pathway can also be initiated by the amyloid-beta complex. AMY3 signaling results in increased import of calcium ions into the cytosol across plasma membrane, increased phosphorylation of ERK1/2, Act, and a PKA regulatory subunit II, as well as increased expression of cFos. 22500019

References

Ontology

GO: Biological Process    QuickGO    AmiGO