secondary piRNA processing

Term ID

GO:0140965

Synonyms

• ping-pong amplification
• ping-pong derived piRNA
• secondary piRNA biogenesis
• secondary PIWI-associated RNA processing

Definition

A process leading to the generation of a functional secondary piRNA, involving a self-perpetuating piRNA loop, often called the ping-pong cycle, in which piRNAs are amplified by pairing with complementary transcripts (for example the transposable element mRNA target). In Drosophila, the processing involves the piwi proteins aubergine and Argonaute 3 and in mice, the piwi proteins Piwil2 and Piwil4. (2)

References

Ontology

GO: Biological Process    QuickGO    AmiGO