Search Ontology:
GO: Cellular Component

neurofibrillary tangle

Term ID
GO:0097418
Synonyms
  • flame-shaped neurofibrillary tangle
  • star-shaped neurofibrillary tangle
Definition
Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. Neurofibrillary tangles contain an abnormally phosphorylated form of a microtubule-associated protein, tau. The shape of these inclusions may resemble a flame or a star.
References
  • NIF_Subcellular:nlx_subcell_20090201
  • NIF_Subcellular:nlx_subcell_20090202
  • NIF_Subcellular:sao2409833926
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes