execution phase of apoptosis

Term ID

GO:0097194

Synonyms

• execution phase of apoptotic process

Definition

A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. 21760595

References

• Reactome:R-HSA-75153

Ontology

GO: Biological Process    QuickGO    AmiGO