endocardial cushion to mesenchymal transition

Term ID

GO:0090500

Synonyms

Definition

A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.

References

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is a type of: cardiac epithelial to mesenchymal transition

cardiac epithelial to mesenchymal transition Show first 5 Terms
has subtype: endocardial cushion to mesenchymal transition involved in cardiac skeleton development endocardial cushion to mesenchymal transition involved in heart chamber septation endocardial cushion to mesenchymal transition involved in heart valve formation

endocardial cushion to mesenchymal transition involved in cardiac skeleton development endocardial cushion to mesenchymal transition involved in heart chamber septation endocardial cushion to mesenchymal transition involved in heart valve formation Show first 5 Terms
negatively regulated by: negative regulation of endocardial cushion to mesenchymal transition

negative regulation of endocardial cushion to mesenchymal transition Show first 5 Terms
positively regulated by: positive regulation of endocardial cushion to mesenchymal transition

positive regulation of endocardial cushion to mesenchymal transition Show first 5 Terms
regulated by: regulation of endocardial cushion to mesenchymal transition

regulation of endocardial cushion to mesenchymal transition Show first 5 Terms

Phenotype

Phenotype caused by Genes