Search Ontology:
GO: Biological Process
negative regulation of canonical Wnt signaling pathway
- Term ID
- GO:0090090
- Synonyms
-
- negative regulation of canonical Wnt receptor signaling pathway
- negative regulation of canonical Wnt receptor signalling pathway
- negative regulation of canonical Wnt-activated signaling pathway
- negative regulation of catenin import into nucleus
- negative regulation of catenin protein nuclear translocation
- negative regulation of Wnt receptor signaling pathway through beta-catenin
- Definition
- Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
- References
-
- Reactome:R-HSA-3772470
- Reactome:R-HSA-4641258
- Ontology
- GO: Biological Process QuickGO AmiGO
- is a type of
-
- negatively regulates
-
Phenotype
Phenotype caused by Genes