Search Ontology:
GO: Biological Process

negative regulation of canonical Wnt signaling pathway

Term ID
GO:0090090
Synonyms
  • negative regulation of canonical Wnt receptor signaling pathway
  • negative regulation of canonical Wnt receptor signalling pathway
  • negative regulation of canonical Wnt-activated signaling pathway
  • negative regulation of catenin import into nucleus
  • negative regulation of catenin protein nuclear translocation
  • negative regulation of Wnt receptor signaling pathway through beta-catenin
Definition
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
References
  • Reactome:R-HSA-3772470
  • Reactome:R-HSA-4641258
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is a type of
negatively regulates
Phenotype
Phenotype caused by Genes