Search Ontology:
GO: Cellular Component

BRCA1-A complex

Term ID
GO:0070531
Synonyms
Definition
A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites. 19261749
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes
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