growth hormone receptor signaling pathway via JAK-STAT

Term ID

GO:0060397

Synonyms

• JAK-STAT cascade involved in growth hormone signalling pathway

Definition

The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes. 11445442

References

Ontology

GO: Biological Process    QuickGO    AmiGO