large conductance calcium-activated potassium channel activity

Term ID

GO:0060072

Synonyms

• BK calcium-activated potassium channel activity
• BK channel activity
• BK KCa channel activity
• large conductance KCa channel activity

Definition

Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. (2)

References

Ontology

GO: Molecular Function    QuickGO    AmiGO