saccharopine dehydrogenase (NADP+, L-lysine-forming) activity

Term ID

GO:0047130

Synonyms

• 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)
• L-lysine-alpha-ketoglutarate reductase activity
• lysine:alpha-ketoglutarate:TPNH oxidoreductase (epsilon-N-[gultaryl-2]-L-lysine forming)
• N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)
• saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase activity

Definition

Catalysis of the reaction: L-saccharopine + H2O + NADP+ = 2-oxoglutarate + L-lysine + H+ + NADPH. 1.5.1.8

References

• EC:1.5.1.8
• KEGG_REACTION:R00716
• MetaCyc:1.5.1.8-RXN
• RHEA:19373
• Reactome:R-HSA-70938

Ontology

GO: Molecular Function    QuickGO    AmiGO